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Knowledge-based grouping of canonical pathways that were significantly enriched for CAD genetic loci.

Journal: PLoS Genetics

Article Title: Integrative Genomics Reveals Novel Molecular Pathways and Gene Networks for Coronary Artery Disease

doi: 10.1371/journal.pgen.1004502

Figure Lengend Snippet: Knowledge-based grouping of canonical pathways that were significantly enriched for CAD genetic loci.

Article Snippet: Our first aim was to test if any of the known biological pathways curated in Reactome, Biocarta and Kyoto Encyclopedia of Genes and Genomes (KEGG) databases , was more likely to harbor tissue-specific eSNPs that were also associated with CAD in GWAS ( ).

Techniques: